... } ... ) >>> df Animal Speed 0 Falcon 100 1 Parrot 5 2 Falcon 200 3 Falcon 300 4 Parrot 15 >>> df.groupby(pd.Grouper(key="Animal")).mean() Speed Animal Falcon 200.0 Parrot 10.0 Specify a resample operation on the column 'Publish date' >>> df = pd.DataFrame( ... { ... "Publish date": [ ... pd.Timestamp("2000-01-02"), ... pd.Timestamp("2000-01-02"), ... pd.Timestamp("2000-01-09"), ... pd.Timestamp("2000-01-16") ... ], ... "ID": [0, 1, 2, 3], ... "Price": [10, 20, 30, 40] ... } ... ) >>> df Publish date ID Price 0 2000-01-02 0 10 1 2000-01-02 1 20 2 2000-01-09 2 30 3 2000-01-16 3 40 >>> df.groupby(pd.Grouper(key="Publish date", freq="1W")).mean() ID Price Publish date 2000-01-02 0.5 15.0 2000-01-09 2.0 30.0 2000-01-16 3.0 40.0 If you want to adjust the start of the bins based on a fixed timestamp: >>> start, end = '2000-10-01 23:30:00', '2000-10-02 00:30:00' >>> rng = pd.date_range(start, end, freq='7min') >>> ts = pd.Series(np.arange(len(rng)) * 3, index=rng) >>> ts 2000-10-01 23:30:00 0 2000-10-01 23:37:00 3 2000-10-01 23:44:00 6 2000-10-01 23:51:00 9 2000-10-01 23:58:00 12 2000-10-02 00:05:00 15 2000-10-02 00:12:00 18 2000-10-02 00:19:00 21 2000-10-02 00:26:00 24 Freq: 7T, dtype: int64 >>> ts.groupby(pd.Grouper(freq='17min')).sum() 2000-10-01 23:14:00 0 2000-10-01 23:31:00 9 2000-10-01 23:48:00 21 2000-10-02 00:05:00 54 2000-10-02 00:22:00 24 Freq: 17T, dtype: int64 >>> ts.groupby(pd.Grouper(freq='17min', origin='epoch')).sum() 2000-10-01 23:18:00 0 2000-10-01 23:35:00 18 2000-10-01 23:52:00 27 2000-10-02 00:09:00 39 2000-10-02 00:26:00 24 Freq: 17T, dtype: int64 >>> ts.groupby(pd.Grouper(freq='17min', origin='2000-01-01')).sum() 2000-10-01 23:24:00 3 2000-10-01 23:41:00 15 2000-10-01 23:58:00 45 2000-10-02 00:15:00 45 Freq: 17T, dtype: int64 If you want to adjust the start of the bins with an `offset` Timedelta, the two following lines are equivalent: >>> ts.groupby(pd.Grouper(freq='17min', origin='start')).sum() 2000-10-01 23:30:00 9 2000-10-01 23:47:00 21 2000-10-02 00:04:00 54 2000-10-02 00:21:00 24 Freq: 17T, dtype: int64 >>> ts.groupby(pd.Grouper(freq='17min', offset='23h30min')).sum() 2000-10-01 23:30:00 9 2000-10-01 23:47:00 21 2000-10-02 00:04:00 54 2000-10-02 00:21:00 24 Freq: 17T, dtype: int64 To replace the use of the deprecated `base` argument, you can now use `offset`, in this example it is equivalent to have `base=2`: >>> ts.groupby(pd.Grouper(freq='17min', offset='2min')).sum() 2000-10-01 23:16:00 0 2000-10-01 23:33:00 9 2000-10-01 23:50:00 36 2000-10-02 00:07:00 39 2000-10-02 00:24:00 24 Freq: 17T, dtype: int64 Ú