s=['A', 'B', 'C']) >>> df A B C 0 0 2 3 1 0 4 1 2 10 20 30 Get value at specified row/column pair >>> df.iat[1, 2] 1 Set value at specified row/column pair >>> df.iat[1, 2] = 10 >>> df.iat[1, 2] 10 Get value within a series >>> df.loc[0].iat[1] 2 Ú